Potential Coronavirus Treatment – Led by Mark Pimentel, MD, the research team of the Medically Associated Science and Technology (MAST) Program at Cedars-Sinai has been developing the patent-pending Healight platform since 2016 and has produced a growing body of scientific evidence demonstrating pre-clinical safety and effectiveness of the technology as an antiviral and antibacterial treatment. The Healight technology employs proprietary methods of administering intermittent ultraviolet (UV) A light via a novel endotracheal medical device. Pre-clinical findings indicate the technology’s significant impact on eradicating a wide range of viruses and bacteria, inclusive of coronavirus. The data have been the basis of discussions with the FDA for a near-term path to enable human use for the potential treatment of coronavirus in intubated patients in the intensive care unit (ICU). Beyond the initial pursuit of a coronavirus ICU indication, additional data suggest broader clinical applications for the technology across a range of viral and bacterial pathogens. This includes bacteria implicated in ventilator associated pneumonia (VAP).
Coronavirus: Robots use light beams to zap hospital viruses
Ultraviolet Blood Treatment. A simple intravenous therapy that exposes blood to specific ultraviolet light as a natural antibiotic to enhance the body’s ability to fight infections
Inactivation of viruses during ultraviolet light treatment of human intravenous immunoglobulin and albumin. The use of UV irradiation to inactivate infectious agents could add safety and supplement current methods, e.g. solvent/detergent, low pH, which do not inactivate non-enveloped, non-acid labile or dry-heat-resistant viruses at present.
Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases. “A direct approach to prevent airborne transmission is inactivation of airborne pathogens, and the airborne antimicrobial potential of UVC ultraviolet light has long been established; however, its widespread use in public settings is limited because conventional UVC light sources are both carcinogenic and cataractogenic. By contrast, we have previously shown that far-UVC light (207–222 nm) efficiently inactivates bacteria without harm to exposed mammalian skin. This is because, due to its strong absorbance in biological materials, far-UVC light cannot penetrate even the outer (non living) layers of human skin or eye; however, because bacteria and viruses are of micrometer or smaller dimensions, far-UVC can penetrate and inactivate them. We show for the first time that far-UVC efficiently inactivates airborne aerosolized viruses, with a very low dose of 2 mJ/cm2 of 222-nm light inactivating >95% of aerosolized H1N1 influenza virus. Continuous very low dose-rate far-UVC light in indoor public locations is a promising, safe and inexpensive tool to reduce the spread of airborne-mediated microbial diseases.”
Effect of far ultraviolet light emitted from an optical diffuser on methicillin-resistant Staphylococcus aureus in vitro.
Other resources:
[1] Downes, A. Researches on the effect of light upon bacteria and other organisms. Proc Roy Soc Med 1877;26:488. Cited in Kime, Z. sun Could Save Your Life. World Health Publications, Penryn, CA 1980:126-30.
[2] Miley, G. The Knott technic of ultraviolet blood irradiation in acute pyogenic infections. New York J Med 1942;42:38.
[3] Miley, G. The Knott technic of ultraviolet blood irradiation in acute pyogenic infections. New York J Med 1942;42:38.
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[4] Rebbeck, E. Ultraviolet irradiation of auto-transfused blood in the treatment of puerperal sepsis. Amer J Surg 1941;54:691
[5] Rebbeck, E. Ultraviolet irradiation of autotransfused blood in the treatment of postabortal sepsis. Amer J Surg 1942;55:476.
[6] Rebbeck, E. Ultraviolet irradiation of the blood in the treatment of escherichia coli septicemia. Arch Phys Ther 1943;24:158.
[7] Rebbeck, E. The Knott technic of ultraviolet blood irradiation as a control of infection in peritonitis. Amer J Gastroenterol 1943;10:1-26
[8] Hancock, V. Irradiated blood transfusions in the treatment of infections. Northwest Med 1934;33:200.
[9] Barrett, H. Five years experience with hemo-irradiation according to the Knott technic. Am J Surg 1943;61:42
[10] Barrett, H. The irradiation of auto-transfused blood by ultraviolet spectral energy: results of therapy in 110 cases. Med Clin N Amer 1940;24:723
[11] Miley, G. The present status of ultraviolet blood irradiation. Arch Phys Ther 1944;25:357.
[12] Hollaender, A. The inactivating effect of monochromatic ultraviolet radiation on influenza virus. J Bact 1944;48:447.
[13] Heding LD, Schaller JP, Blakeslee JR, Olsen RG.Inactivation of tumor cell-associated feline oncornavirus for preparation of an infectious virus-free tumor cell immunogen. Cancer Res 1976;36:1647.
[14] Hart, D. Sterilization of the air in the operating room by special antibacterial radiant energy. J Thorac Cardiovasc Surg 1936;6:45.
[15]Gameson, A. Field studies on effect of daylight on mortality of coliform bacteria. Water Res 1967;1:279.
You can take it from here and find tons more if you care, the point is made. In the words of a knowledgeable Facebook commentator “Folks, be careful not to dismiss information just because you don’t like who is saying it.”
To be continued?
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